主な発表論文
〈 筆 頭 〉
Aihara T, Kumamaru H, Ishitobi M, Miyashita M, Miyata H, Tamura K, Yoshida M, Ogo E, Nagahashi M, Asaga S, Kojima Y, Kadoya T, Aogi K, Niikura N, Iijima K, Hayashi N, Kubo M, Yamamoto Y, Takeuchi Y, Imoto S, Jinno H.Prognosis and effectiveness of chemotherapy for medullary breast carcinoma
（Breast Cancer Res Treat. 2022 Dec;196(3):635-645）
Aihara T, Toyama T, Takahashi M, Yamamoto Y, Hara F, Akabane H, Fujisawa T, Ishikawa T, Nagai S, Nakamura R, Tsurutani J, Ito Y, Mukai H.
The Japanese Breast Cancer Society Clinical Practice Guideline for systemic treatment of breast cancer, 2015 edition.
（Breast Cancer. 2016 ;23(3):329-42.）
Aihara T, Yokota I, Hozumi Y, Aogi K, Iwata H, Tamura M, Fukuuchi A, Makino H, Kim R, Andoh M, Tsugawa K, Ohno S, Yamaguchi T, Ohashi Y, Watanabe T, Takatsuka Y, Mukai H.
Anastrozole versus tamoxifen as adjuvant therapy for Japanese postmenopausal patients with hormone-responsive breast cancer: efficacy results of long-term follow-up data from the N-SAS BC 03 trial.
（Breast Cancer Res Treat.2014;148(2):337-43.）
Aihara T, Tanaka S, Sagara Y, Iwata H, Hozumi Y, Takei H, Yamaguchi H, Ishitobi M, Egawa C.
Incidence of contralateral breast cancer in Japanese patients with unilateral minimum-risk primary breast cancer, and the benefits of endocrine therapy and radiotherapy.
（Breast Cancer 2014;21(3):284-91.）
Aihara T, Mukai H.
The current status and future perspectives of CSPOR-BC.
（Breast Cancer 2013;20(4):287-90.）
Aihara T, Suemasu K, Takei H, Hozumi Y, Takehara M, Saito T, Ohsumi S, Masuda N, Ohashi Y.
Effects of exemestane, anastrozole and tamoxifen on bone mineral density and bone turnover markers in postmenopausal early breast cancer patients:results of N-SAS BC 04, the TEAM Japan substudy.
（Oncology.2010;79(5-6):376-81.）
Aihara T, Takatsuka Y, Ohsumi S, Aogi, K, Hozumi Y, Imoto S, Mukai H, Iwata H, Watanabe T, Shimizu C, Nakagami K, Tamura M, Ito T, Masuda N, Ogino N, Hisamatsu K, Mitsuyama S, Abe H, Tanaka S, Yamaguchi T, Ohashi Y.
Phase III Randomized Adjuvant Study of Tamoxifen Alone Versus Sequential Tamoxifen and Anastrozole in Japanese Postmenopausal Women with Hormone-Responsive Breast Cancer: N-SAS BC03 Study.
（Breast Cancer Research and Treatment 2010;121(2):379-87.）
Aihara T, Munakata S, Morino H, Takatsuka Y.
Comparison of frozen section and touch imprint cytology for evaluation of sentinel lymph node metastasis in breast cancer.
（Ann Surg Oncol 2004;11(8):747-50.）
Aihara T, Munakata S, Morino H, Takatsuka Y.
Feasibility of sentinel node biopsy for breast cancer after neoadjuvant endocrine therapy: a pilot study.
（J Surg Oncol.2004 ;85(2):77-81.）
Aihara T, Munakata S, Morino H, Takatsuka Y.
Touch imprint cytology and immunohistochemistry for the assessment of sentinel lymph nodes in patients with breast cancer.
（Eur J Surg Oncol.2003 ;29(10):845-8.）
Aihara T, Takatsuka Y.
Dye-guided sentinel node biopsy revisited; validation and observational study from a single institute.
（Breast Cancer.2003;10(3):254-9.）
Aihara T, Takatsuka Y, Itoh K, Sasaki Y, Katsumata N, Watanabe T, Noguchi S, Horikoshi N, Tabei T, Sonoo H, Hiraki S, Inaji H.
Phase II study of concurrent administration of doxorubicin and docetaxel as first-line chemotherapy for metastatic breast cancer.
（Oncology.2003;64(2):124-30.）
Aihara T, Kim Y, Takatsuka Y.
Phase II study of weekly docetaxel in patients with metastatic breast cancer.
（Ann Oncol.2002;13(2):286-92.）
Aihara T, Fujiwara Y, Miyake Y, Okami J, Okada Y, Iwao K, Sugita Y, Tomita N, Sakon M, Shiozaki H, Monden M.
Mammaglobin B gene as a novel marker for lymph node micrometastasis in patients with abdominal cancers.
（Cancer Lett.2000;150(1):79-84.）
Aihara T, Fujiwara Y, Ooka M, Sakita I, Tamaki Y, Monden M.
Mammaglobin B as a novel marker for detection of breast cancer micrometastases in axillary lymph nodes by reverse transcription-polymerase chain reaction.
（Breast Cancer Res Treat.1999;58(2):137-40.）〈 共 著 〉
Tsurutani J,Hara F, Kitada M, Takahashi M, Kikawa Y, Kato H, Sakata E, Naito Y, Hasegawa Y, Saito T, Iwasa T, Taira N, Takashima T, Kashiwabara K, Aihara T, Mukai H.Randomized phase II study to determine the optimal dose of 3-week cycle nab-paclitaxel in patients with metastatic breast cancer.
(The Breast,55,2021,63-68)
Ishikawa T,Sakamaki K, Narui K, Nishimura H, Sangai T, Tamaki K, Hasegawa Y, Watanabe KI, Suganuma N, Michishita S, Sugae S, Aihara T, Tsugawa K, Kaise H, Taira N, Mukai H
Prospective cohort study of febrile neutropenia in breast cancer patients administered with neoadjuvant and adjuvant chemotherapies: CSPOR-BC FN study
(The Breast,56,2021,70-77)
Iwamoto T, Taira N, Fujisawa T, Araki K, Sakamaki K, Sangai T, Kikawa Y, Shien T, Takao S, Sato M, Goto Y, Yoshida T, Takahashi M, Aihara T, Mukai H.
Hormonal Therapy Resistant Estrogen-receptor Positive Metastatic Breast Cancer Cohort (HORSE-BC) Study : Current Status of Treatment Selection in Japan.
（Acta Med Okayama. 2018 Aug;72(4):369-374.）
Shimoi T, Shimomura A, Shien T, Uemura Y, Kato H, Kitada M, Toyama T, Aihara T, Mukai H.
Open-label Phase II study of everolimus plus endocrine therapy in postmenopausal women with ER-positive and HER2-negative metastatic breast cancer (Chloe trial).
（Open Access Journal of Clinical Trials 2018:10 13-18）
Hara F, Takashima T, Tsurutani J, Saito T, Taira N, Kashiwabara K, Aihara T, Mukai H.
Randomized, Optimal Dose Finding, Phase Ii Study of Tri-Weekly Nab-Paclitaxel in Patients with Metastatic Breast Cancer (ABROAD).
（J Clin Trials 2016, 6:3.）
Dowsett M, Forbes JF, Bradley R, Ingle J, Aihara T, Bliss J, Boccardo F, Coates A, Coombes RC, Cuzick J, Dubsky P, Gnant M, Kaufmann M, Kilburn L, Perrone F, Rea D, Thurlimann B, van de Velde C, Pan H, Peto R, Davies C, Gray R.
Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials.
（Lancet. 2015;386(10001):1341-52.）
Kimura K, Iwamoto M, Tanaka S, Watanabe T, Aihara T, Sugimoto T, Miyara K, Hayashi M, Kouno T, Baba S, Kawashima H, Hashimoto N, Uchiyama K.
Is the LHRH Agonist Recommended for Fertility Preservation ?
（Gan To Kagaku Ryoho. 2015 ;42(8):1019-21. (in Japanese).）
Mukai H, Aihara T, Yamamoto Y, Takahashi M, Toyama T, Sagara Y, Yamaguchi H, Akabane H, Tsurutani J, Hara F, Fujisawa T, Yamamoto N, Ohsumi S.
The Japanese Breast Cancer Society Clinical Practice Guideline for systemic treatment of breast cancer.
（Breast Cancer. 2015;22(1):5-15.）
Miyake T, Aihara T, Noguchi S.
Diagnosis of metachronous bilateral breast cancer.
（Nihon Rinsho.2012;70 Suppl 7:284-7. (in Japanese)）
Oyama A, Ueno T, Uchiyama S, Aihara T, Miyake A, Kondo S, Matsunaga K.
The effects of natural S-equol supplementation on skin aging in postmenopausal women: a pilot randomized placebo-controlled trial.
（Menopause.2012;19(2):202-10.）
Hozumi Y, Suemasu K, Takei H, Aihara T, Takehara M, Saito T, Ohsumi S, Masuda N, Ohashi Y.
The effect of exemestane, anastrozole, and tamoxifen on lipid profiles in Japanese postmenopausal early breast cancer patients: final results of National Surgical Adjuvant Study BC 04, the TEAM Japan sub-study.
（Ann Oncol.2011;22(8):1777-82.）
Ohsumi S, Shimozuma K, Ohashi Y, Shinji M, Hozumi Y, Mukai H, Takatsuka Y, Aihara T.
Health-related quality of life and psychological distress of breast cancer patients after surgery during a phase III randomized trial comparing continuation of tamoxifen with switching to anastrozole after adjuvant tamoxifen for 1-4 years: N-SAS BC 03.
（Breast Cancer Res Treat 2011;127(1):143-52.）The marriage, pregnancy, childbirth on the breast cancer--psychologic care.
（Nippon Rinsho.2006;64(3):575-80(in Japanese). ）
Taguchi T, Aihara T, Takatsuka Y, Shin E, Motomura K, Inaji H, Noguchi S.
Phase II study of weekly paclitaxel for docetaxel-resistant metastatic breast cancer in Japan.
（Breast J 2004;10(6):509-13.）
Munakata S, Aihara T, Morino H, Takatsuka Y.
Application of immunofluorescence for intraoperative evaluation of sentinel lymph nodes in patients with breast carcinoma.
（Cancer. 2003 ;98(8):1562-8.）
Noguchi S, Hiratsuka M, Furukawa H, Aihara T, Kasugai T, Tamura S, Imaoka S, Koyama H, Iwanaga T.
Detection of gastric cancer micrometastases in lymph nodes by amplification of keratin 19 mRNA with reverse transcriptase-polymerase chain reaction.
（Jpn J Cancer Res 1996;87(6):650-4.）
Noguchi S, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H.
ペリネイタルケア ２００５年８月号
Histologic characteristics of breast cancers with occult lymph node metastases detected by keratin 19 mRNA reverse transcriptase-polymerase chain reaction.
（Cancer.1996;78(6):1235-40.）
Noguchi S, Aihara T, Yoshino K, Motomura K, Inaji H, Imaoka S, Koyama H.
Demonstration of monoclonal origin of human parotid gland pleomorphic adenoma.
（Cancer.1996;77(3):431-5.）
Noguchi S, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H, Kasugai T, Wada A.
Phyllodes Tumor of the Breast: Pathology, Histogenesis, Diagnosis, and Treatment.
（Breast Cancer.1996;3(2):79-92.）
Noguchi S, Aihara T, Motomura K, Inaji H, Koyama H.
Detection of breast cancer micrometastases in lymph nodes by amplification of keratin 19 mRNA with reverse-transcriptase polymerase chain reaction.
（Gan To Kagaku Ryoho.1996;23 Suppl 1:50-5(in Japanese).）
Noguchi S, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H.
Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Comparison between MUC1 mRNA and keratin 19 mRNA amplification.
（Am J Pathol 1996;148(2):649-56.）
Noguchi S, Aihara T, Koyama H, Motomura K, Inaji H, Imaoka S.
Clonal analysis of benign and malignant human breast tumors by means of polymerase chain reaction.
（Cancer Lett 1995;90(1):57-63.）
Noguchi S, Yokouchi H, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H.
Progression of fibroadenoma to phyllodes tumor demonstrated by clonal analysis.
（Cancer.1995;76(10):1779-85.）
Noguchi S, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H, Tanaka H.
Demonstration of polyclonal origin of giant fibroadenoma of the breast.
（Virchows Arch.1995;427(3):343-7.）
Noguchi S, Aihara T, Nakamori S, Motomura K, Inaji H, Imaoka S, Koyama H.
The detection of breast carcinoma micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction.
（Cancer.1994;74(5):1595-600.）
Noguchi S, Aihara T, Koyama H, Motomura K, Inaji H, Imaoka S.
Discrimination between multicentric and multifocal carcinomas of the breast through clonal analysis.
（Cancer .1994;74(3):872-7.）
Noguchi S, Aihara T, Motomura K, Inaji H, Koyama H.
Clonal analysis of human breast tumors by means of polymerase chain reaction.
（Gan To Kagaku Ryoho.1994;21 Suppl 2:164-7(in Japanese).）
Noguchi S, Aihara T, Koyama H, Motomura K, Inaji H, Imaoka S, Wada A.
Preoperative discrimination of fibroadenoma which is clinically and cytologically indistinguishable from breast carcinoma through clonal analysis of fine needle aspirate of tumor: Report of a case.
（Breast Cancer.1994;1(1):37-42.）
産褥期の腫瘍性疾患への対応
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